Is ANNX Worth Buying in 2026?

Annexon, Inc. Common Stock

STOCK PHARMACEUTICAL PREPARATIONS Updated 2026-06-14

Here’s whether Annexon, Inc. Common Stock (ANNX) is worth buying in 2026 — based on weekly-updated price trend, RSI momentum, and return vs. the S&P 500. Our current read: Neutral.

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Neutral

Positives: trading above the 200-day MA (long-term uptrend intact); RSI 35 — healthy momentum range; strong 1-year return of +73.8%; rising volume confirms the move (1.18x 30d avg). Concerns: below the 50-day MA (medium-term momentum negative); 50-day MA is falling (-0.36% over 10 days); 3-month momentum negative (-17.7%). Currently 34.4% off its 52-week high. Score: +2/7.

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ANNX is holding above its long-term 200-day MA ($4.67) but has slipped below the 50-day MA ($5.62), pointing to short-term weakness in an otherwise intact trend. An RSI of 35.0 sits in the neutral zone — momentum is neither stretched nor exhausted. The 1-year return of +73.8% compares to +22.9% for SPY (beat the market by 50.9%). The current 34.4% drawdown from the 52-week high reflects elevated risk for momentum-based strategies.

$10,000 invested 1 year ago → $17,380 today
vs. S&P 500 (SPY) — same period beat market by 50.9%

1-Year Price Chart

Daily candles
MA-50 MA-200 Up Down

Signal Check

Above 200-day MA ($4.67)
Above 50-day MA ($5.62)
RSI(14) neutral zone (30–70) — currently 35.0
Positive return (+73.8%)
!Within 10% of period high (−34.4%)
Period Range $4.71
$1.85 $7.18
RSI (14) 35.0
0 · OversoldOverbought · 100

Key Metrics

Price$4.71
Period Return+73.8%
Period High$7.18
Period Low$1.85
Drawdown−34.4%
MA-50$5.62
MA-200$4.67
RSI (14)35.0
Avg Volume (30d)2.4M
vs. SPYbeat by 50.9%
Return Rank#250 of 1246

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